Immune system development linked to leukemia
Scientists have discovered a genetic signature that implicates a key mechanism in the immune system as a driving force for a type of childhood leukaemia.
Jan 12, 2014
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Scientists have discovered a genetic signature that implicates a key mechanism in the immune system as a driving force for a type of childhood leukaemia.
Jan 12, 2014
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Cancer biologists are yet to understand the mechanisms and cellular hierarchy leading to the developmental arrest in rhabdomyosarcoma (RMS)—a group of pediatric cancers, which remain enigmatic.
In a major triumph for personalized medicine, the FDA approved the drug crizotinib for use with the lung cancer type known as ALK-positive.
Aug 31, 2011
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To find new treatment approaches for childhood cancer, scientists at St. Jude Children's Research Hospital are digging deep into disease biology to target a process long considered "undruggable." The approach revealed a new ...
Jul 13, 2022
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Despite years of research, cellular mechanisms contributing to cancers like esophageal adenocarcinoma have remained elusive. What has puzzled researchers was how genes in the healthy cells lining the esophagus turned the ...
Aug 26, 2016
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Researchers at Columbia University Medical Center (CUMC) have discovered that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two adjacent genes. The study ...
Jul 26, 2012
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About half of prostate cancers have a genetic anomaly that appears to make tumor cells responsive to a new class of cancer-fighting drugs, a new study from the University of Michigan Comprehensive Cancer Center finds.
May 18, 2011
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Smoking is a well-known risk factor for lung cancer, but nearly 25% of all lung cancer patients have never smoked. In a study published online today in Genome Research, researchers have identified a previously unknown gene ...
Dec 22, 2011
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A collaborative expedition into the deep genetics of prostate cancer has uncovered a distinct subtype of the disease, one that appears to account for up to 15 percent of all cases, say researchers at Weill Cornell Medical ...
May 20, 2012
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Catastrophic rearrangements in the genome occurring as early as childhood and adolescence can lead to the development of lung cancer in later years in non-smokers. This finding, published in Cell, helps explain how some non-smoking-related ...
May 31, 2019
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