The targeted therapy pralsetinib appears to have high response rates and durable activity in patients with a broad variety of tumors harboring RET gene fusions, according to results from the international Phase I/II ARROW ...
May 29, 2020
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B-cell acute lymphoblastic leukemia (B-ALL) is one of the most common forms of childhood cancer. The overall survival rate is more than 80%, but not in all subtypes; in leukemia with the highest incidence among infants, in ...
Sep 27, 2023
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(Medical Xpress)—In about half of all prostate tumours, there are two genetic areas that are fused with one another. When this is not the case, the exact way cancer cells originate in prostate tumours was not clear until ...
Sep 5, 2012
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Singapore scientists from A*STAR's Genome Institute of Singapore (GIS) and Institute of Molecular and Cell Biology (IMCB), together with colleagues from the National University Health System (NUHS) and Tan Tock Seng Hospital, ...
Jul 7, 2015
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Predicting the course of prostate cancer is challenging because only a fraction of prostate cancer patients experience recurrence after radical prostatectomy or radiation therapy. Yet, prostate cancer remains one of the most ...
Feb 14, 2023
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Analysis of the entire tumor RNA picks up more clinically relevant genetic changes in children with cancer than traditional diagnostic methods, new research has shown.
Jan 27, 2022
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(Medical Xpress)—Scientists have mapped the genetic changes that drive tumors in rhabdomyosarcoma, a pediatric soft-tissue cancer, and found that the disease is characterized by two distinct genotypes. The genetic alterations ...
Jan 23, 2014
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A novel assay that detects a unique molecular marker in patients with acute myeloid leukemia (AML) may revolutionize the way this disease is detected and treated according to a new report in The Journal of Molecular Diagnostics. ...
Nov 13, 2023
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Researchers from the University Health Network (UHN); Toronto Western Neurosurgery Division and MacFeeters Hamilton Neuro-oncology Program at the Princess Margaret Cancer Centre have described the genomic landscape of schwannomas ...
Oct 11, 2016
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An assay that identifies a peculiar but important abnormality in cancer cells has been developed and validated by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and ...
Aug 14, 2017
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