Medical research

Receptors under flow: Mechanosensitive GPCRs

An LMU team has clarified how a receptor which is involved in the regulation of vital physiological processes senses the mechanical forces that act on blood vessels. The findings could suggest new therapies for diseases of ...

Medical research

Key drug target shown assembling in real-time

Over one-third of all FDA-approved drugs act on a specific family of proteins: G-protein coupled receptors (GPCRs). Drugs to treat high blood pressure, asthma, cancer, diabetes and myriad other conditions target GPCRs throughout ...

Genetics

Pathway contributing to fatty liver disease discovered

Researchers from Karolinska Institutet in Sweden have found a protein that is a critical regulator in the development of fatty liver disease in mice, according to a study published in the journal Nature Communications.

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