Surgery

Pre-op pregabalin best for pain in spinal surgery

(HealthDay)—Preoperative pregabalin is superior to either gabapentin or placebo for the relief of pain in patients undergoing lumbar discectomy, according to a study published in the March 15 issue of Spine.

Diseases, Conditions, Syndromes

Drugs may help relieve restless legs syndrome

(HealthDay)—People suffering from restless legs syndrome may find some relief by taking one of several drugs approved to treat the condition, a new review confirms.

Surgery

Gabapentin doesn't cut use of morphine post-knee arthroplasty

(HealthDay)—The addition of gabapentin to patient-controlled analgesia (PCA) protocol does not reduce morphine consumption, pain, or opioid-related side effects in patients undergoing total knee arthroplasty, according ...

Medications

Tafamidis: Approval denotes proven added benefit

Tafamidis meglumine (trade name: Vyndaqel) was approved in November 2011 for the treatment of transthyretin amyloidosis in adults. This rare disorder ("orphan disease") is caused by a defective gene and is associated with ...

Medical research

Beating seizures by jamming the cellular circuitry

Research at UC San Francisco has shown for the first time how the commonly prescribed seizure and pain medication, gabapentin, acts inside of cells, opening the door to new, more effective treatments for diseases like epilepsy ...

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