Genetics

A look at how colds and chronic disease affect DNA expression

We're all born with a DNA sequence that encodes (in the form of genes) the very traits that make us, us—eye color, height, and even personality. We think of those genes as unchanging, but in reality, the way they are expressed, ...

Medical research

'CYCLOPS' algorithm spots daily rhythms in cells

Humans, like virtually all other complex organisms on Earth, have adapted to their planet's 24-hour cycle of sunlight and darkness. That circadian rhythm is reflected in human behavior, of course, but also in the molecular ...

Medical research

Defining the role of HDAC6 in regulating heart stiffness

Researchers at the University of Colorado School of Medicine have discovered an enzyme that regulates heart stiffness, setting the stage for developing novel treatments for heart failure.

Genetics

Form of severe malnutrition linked to DNA modification

A group led by researchers at Baylor College of Medicine has identified significant differences at the epigenetic level—the chemical tags in DNA that help regulate gene expression—between two clinically distinct forms ...

Cardiology

ASH: High-dose gene transfer beneficial in severe hemophilia A

(HealthDay)—For men with severe hemophilia A, high-dose factor VIII gene transfer is associated with sustained normalization of factor VIII activity levels, according to a study published online Dec. 9 in the New England ...

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