Medical research

Solving the puzzle of necroptosis

Cell death is an essential physiological process for all multicellular organisms. Throughout life, cells in many tissues die naturally and are replaced by new cells. A proper balance between the death and production of new ...

Genetics

Scientists edit gene mutations in inherited form of anemia

A Yale-led research team used a new gene editing strategy to correct mutations that cause thalassemia, a form of anemia. Their gene editing technique provided corrections to the mutations and alleviated the disease in mice, ...

Medical research

Genome engineering paves the way for sickle cell cure

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of ...

Medical research

Video: CRISPR puts up a fight against persistent herpesviruses

Since its development, CRISPR technology has been applied a range of scientific inquiries, spanning from the genomic editing of Florida orange crops to Zebrafish. In work recently published in PLOS Pathogens, Robert Jan Lebbink ...

Genetics

Genome-editing 'toolbox' targets multiple genes at once

A Yale research team has designed a system to modify, or edit, multiple genes in the genome simultaneously, while also minimizing unintended effects. The gene-editing "toolbox" provides a user-friendly solution that scientists ...

Genetics

Chinese team to pioneer first human CRISPR trial

(Medical Xpress)—A team of researchers at Sichuan University's West China Hospital has announced plans to begin a clinical trial where cells modified using the CRISPR gene editing technique will be used on human beings ...

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