Researchers at Dana-Farber/Children's Hospital Cancer Center (DF/CHCC) and several collaborating institutions have linked mutations in specific genes to each of the four recognized subtypes of medulloblastoma, the most common ...
Jul 22, 2012
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Scientists from the Precision Cardiology Lab (PCL) of the Broad Institute of MIT and Harvard and Bayer have generated detailed maps of a variety of cell types in the heart that are involved in two major causes of heart failure: ...
Jun 23, 2022
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Researchers at the Broad Institute of MIT and Harvard and Massachusetts General Hospital have constructed a high-resolution cellular map of Crohn's disease, a chronic condition in which a hyperactive immune system causes ...
Jan 31, 2023
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Aspirin has been widely used for more than 50 years as a common, inexpensive blood thinner for patients with heart disease and stroke, but doctors have little understanding of how it works and why some people benefit and ...
Jul 3, 2013
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A new method by researchers in the UK and Belgium makes it possible to study the epigenome and transcriptome of a single cell at the same time. The protocol, published in Nature Methods, helps scientists pinpoint the relationship ...
Jan 11, 2016
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According to new research published in The FASEB Journal, a drop in blood zinc levels does not directly harm the blood vessel cells. Rather, zinc regulates the production of a small molecular compound, which then circulates ...
Aug 29, 2013
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Cutaneous melanoma, the most aggressive form of skin cancer, is the fifth most diagnosed cancer in Europe and one of the most frequent causes of cancer death, with incidence and mortality trends on the rise. While the development ...
Apr 20, 2023
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Last year Broad researchers described a single-nucleus RNA sequencing method called sNuc-Seq. This system enabled researchers to study the gene expression profiles of difficult-to-isolate cell types as well as cells from ...
Aug 28, 2017
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Crohn's and other inflammatory bowel diseases (IBDs) can be painful and debilitating. There are no known cures for these diseases, but the symptoms can be managed. It is widely thought that IBDs develop as a result of an ...
Jul 8, 2014
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One of the big challenges in neurobiology is cell classification, a problem compounded by the fact that the same cell type can look different depending on the method of analysis used to classify it—whether by cell shape, ...
Jan 28, 2019
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