Researchers led by the University of California, Irvine have discovered how the TREM2 R47H genetic mutation causes certain brain areas to develop abnormal protein clumps, called beta-amyloid plaques, associated with late-onset ...
4 hours ago
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To effectively treat a disease or disorder, doctors must first know the root cause. Such is the case for developmental and epileptic encephalopathies (DEEs), whose root causes can be hugely complex and heterogeneous.
10 hours ago
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Northwestern Medicine scientists have discovered new insights into the production and regulation of a class of noncoding RNAs and how alterations in their signatures diversify and modulate the transcriptome of three major ...
Aug 5, 2024
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Eating a vegan diet for eight weeks is associated with reductions in biological age estimations based on levels of DNA methylation—a type of chemical modification of DNA (known as an epigenetic modification) that alters ...
Jul 28, 2024
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A new research paper was published in Oncotarget entitled, "Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma."
Jul 26, 2024
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Non-alcoholic fatty liver disease (NAFLD) has emerged as a leading cause of chronic liver disease worldwide, affecting approximately 38% of the global population from 2016 to 2019. NAFLD is characterized by the accumulation ...
Jul 25, 2024
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Researchers from North Carolina State University have developed an array that assesses methylation levels of genes located in imprint control regions (ICRs) within the human genome. The array represents a cost-effective, ...
Jul 25, 2024
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Researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania revealed the most extensive single cell atlas of the human kidney, capturing the complexity of ...
Jul 25, 2024
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Ultrafine particles, UFPs, the smallest contributors to air pollution, hinder the function of mitochondria in human olfactory mucosa cells, a new study shows. Led by the University of Eastern Finland, the research showed ...
Jul 24, 2024
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Receptor protein tyrosine phosphatases are cell membrane-localized proteins. They are regulators of cell-cell contacts and are also considered likely to be tumor suppressors, but the specifics of how they function are unknown. ...
Jul 24, 2024
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Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as rRNA genes or tRNA genes, the product is a functional RNA.
Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in the organism.
This text uses material from Wikipedia, licensed under CC BY-SA
