Deletion of the HIRA protein promotes the proliferation and invasion of tumor cells in cell culture and animal models. That is the result of a research endeavor led by Alexander von Humboldt Professor Dr. Christian Frezza ...
Oct 26, 2022
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8
Two University of Arizona Health Sciences scientists are one step closer to developing a predictive test to assess a baby's risk for asthma, which would allow parents to take steps to thwart the disease's development and ...
Sep 12, 2022
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A new data-driven mechanistic approach that predicts cell types within tissue will help to reduce drug costs and treat diseases that were difficult to develop drugs for, according to a West Virginia University scientist.
Apr 14, 2022
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A team of researchers at the University of Adelaide has found a link between the way that cells produce energy for brain function and the mutated genes found in Alzheimer's disease.
Dec 27, 2021
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After several decades of pre-clinical development, cell- and gene-based therapies for Parkinson's disease (PD) are now actively being explored. In this special supplement to the Journal of Parkinson's Disease, "Repairing ...
Sep 24, 2021
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Mutations in the ARID1A gene are present in more than 50% of ovarian clear cell carcinomas (OCCC), for which effective treatments are lacking. Scientists at The Wistar Institute discovered that loss of ARID1A function enhances ...
Sep 21, 2021
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KRAS was one of the first oncogenes to be identified, a few decades ago. It is among the most common drivers of cancer and its mutations can be detected in around 25 percent of human tumors. The development of KRAS inhibitors ...
Jul 19, 2021
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Monash University researchers have uncovered for the first time the reason mutations in a particular gene lead to mitochondrial disease.
Apr 27, 2021
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Gut hormones play an important role in regulating fat production in the body. One key hormone, released a few hours after eating, turns off fat production by regulating gene expression in the liver, but this regulation is ...
Nov 24, 2020
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157
Greenwood Genetic Center (GGC) researchers, in collaboration with scientists from Belgium, Spain, and Italy, have confirmed that variants in LMNB1 cause syndromic microcephaly with variable short stature, intellectual disability, ...
Sep 17, 2020
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