Oncology & Cancer

Key gene in leukemia discovered

Acute myeloid leukemia (AML) is one of the most common forms of blood cancer among adults and is associated with a low survival rate, and leads to the inhibition of normal blood formation. Now, a research team at Lund University ...

Immunology

Phosphorylation of Regnase-1 lets IL-17 run amok

When considering the role of the key immune molecule interleukin (IL)-17, the phrase "too much of a good thing" springs to mind. Because unlike some of its more sedate cytokine cousins which studiously direct the immune response ...

Diseases, Conditions, Syndromes

New strategy for untreatable kidney disease: targeting cell energy

The best hope for people with an inherited form of kidney disease that causes kidney failure is dialysis or a kidney transplant. But a study led by Yale researchers reveals a potential strategy for developing new drug therapies ...

Oncology & Cancer

Probing H. pylori cancer protein

Infection with the stomach-dwelling bacterium Helicobacter pylori— particularly strains producing the oncoprotein CagA—is a strong risk factor for gastric cancer.

Genetics

Fear that uproar over gene-edited babies could block science

Scientists working on the frontiers of medicine fear the uproar over the reported births of gene-edited babies in China could jeopardize promising research into how to alter heredity to fend off a variety of disorders.

Genetics

New genome-editing strategy could lead to therapeutics

Researchers at UMass Medical School have developed a genome-editing strategy to correct disease-causing DNA mutations in mouse models of human genetic diseases, according to research published in the Aug. 18 edition of Nature ...

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