Clinical trial design for new cancer therapies has historically been focused on the tissue of origin of a tumor, but a paper from researchers at Memorial Sloan-Kettering Cancer Center published on September 26 in Nature Genetics ...
Sep 27, 2013
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Why is it that, despite consuming the same number of calories, sodium and sugar, some people face little risk of diabetes or obesity while others are at higher risk? A new study by investigators at Brigham and Women's Hospital ...
Nov 20, 2018
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SARS-CoV-2-associated acute kidney injury is not uncommon. Many hospitalized COVID-19 patients—as many as 80% of critically ill COVID-19 patients, according to a current study—develop acute kidney injury, but without ...
Jun 8, 2020
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A genetic analysis led by UT Southwestern Medical Center researchers suggests that most pancreatic cancers harbor genetic alterations that could be targeted by existing drugs, using their genetic features as a roadmap for ...
Apr 9, 2015
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A new screening platform using cells grown directly from tumor biopsy samples may lead to truly individualized treatment strategies that would get around the problem of treatment resistance, which limits the effectiveness ...
Nov 13, 2014
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Thirty-two previously unidentified genetic regions associated with osteoporosis and fracture have been identified by a large, worldwide consortium of researchers, including Stanford Prevention Research Center chief John Ioannidis, ...
Apr 15, 2012
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A new landmark study involving 281 elite athletes from Australia and Belgium has revealed one in six have measurements that would normally suggest reduced heart function.
Dec 18, 2023
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Cancer therapies that target specific genetic abnormalities in tumors have revolutionized treatment possibilities over the past two decades. While quality of life and survival are improved with targeted therapies, relapse ...
Jul 13, 2023
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Two mutations identified in individuals with developmental and epileptic brain disease can be traced back to the same ion channel. Researchers have now elucidated how both independent mutations affect the channel's function: ...
Jun 18, 2020
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Researchers in the Taub Institute at Columbia University Medical Center (CUMC) have identified a mechanism that appears to underlie the common sporadic (non-familial) form of Parkinson's disease, the progressive movement ...
Sep 25, 2012
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