Oncology & Cancer

TrackSig: Unlocking the history of cancer through tumor evolution

A tumor is often made up of different cells, some of which have changed—or evolved—over time and gained the ability to grow faster, survive longer and potentially avoid treatment. These cells, which have an "evolutionary ...

Genetics

New clues into the genetic origins of schizophrenia

The first genetic analysis of schizophrenia in an ancestral African population, the South African Xhosa, appears in the Jan. 31 issue of the journal Science. An international group of scientists conducted the research, including ...

Genetics

Using modern human genetics to study ancient phenomena

We humans are obsessed with determining our origins, hoping to reveal a little of "who we are" in the process. It is relatively simple to trace one's genealogy back a few generations, and there are many companies and products ...

Diabetes

Why is type 2 diabetes an increasing problem?

Contrary to a common belief, researchers have shown that genetic regions associated with increased risk of type 2 diabetes were unlikely to have been beneficial to people at stages through human evolution.

Genetics

Two studies reveal genetic variation driving human evolution

A pair of studies published by Cell Press on February 14th in the journal Cell sheds new light on genetic variation that may have played a key role in human evolution. The study researchers used an animal model to study a ...

Oncology & Cancer

How can evolutionary biology explain why we get cancer?

Over 500 billion cells in our bodies will be replaced daily, yet natural selection has enabled us to develop defenses against the cellular mutations which could cause cancer. It is this relationship between evolution and ...

Medical research

'Benign' malaria key driver of human evolution in Asia-Pacific

The malaria species rampant in the Asia-Pacific region has been a significant driver of evolution of the human genome, a new study has shown. An international team of researchers has shown that Plasmodium vivax malaria, the ...

Genetics

Most mutations come from dad

Humans inherit more than three times as many mutations from their fathers as from their mothers, and mutation rates increase with the father's age but not the mother's, researchers have found in the largest study of human ...

Oncology & Cancer

Scientists map genetic evolution of leukemia

The diagnosis of myelodysplastic syndrome, a blood cancer, often causes confusion. While some patients can be treated with repeated blood transfusions, others require chemotherapy, leaving some uncertainty about whether the ...

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