Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth. The resulting ...
Apr 11, 2019
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Our DNA is under constant attack. The delicate molecule that contains our genetic information is extremely vulnerable to everything from environmental agents, such as radiation, to the chemicals in the air we breathe and ...
Jan 10, 2019
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Scientists have put precise timings on the history of a patient's cancer for the first time, effectively 'carbon dating' the different stages in the disease's progression.
May 10, 2017
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Scientists at the Francis Crick Institute have described the molecular structure of a key tumour suppressor protein and provided insights into its role in cells.
Jan 11, 2017
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E-cigarette vapour does not induce DNA mutations commonly observed with tobacco smoke exposures in lab-based tests.
Nov 4, 2016
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Researchers in the UC Department of Cancer Biology have found new protein players that help keep genome stability—a promising finding with the potential to help with the development of new targeted therapeutics in diseases ...
Mar 10, 2015
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Cancerous tumors may be poised at the edge of their own destruction, an insight that could help researchers find new, more effective treatments, suggest SFI External Professor Ricard Solé and colleagues in an April 9 paper ...
Apr 24, 2014
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Scientists studying cancer development have known about micronuclei for some time. These erratic, small extra nuclei, which contain fragments, or whole chromosomes that were not incorporated into daughter cells after cell ...
Jul 9, 2013
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(Medical Xpress)—Researchers at The Jackson Laboratory have identified a molecule that prevents repair of some cancer cells, providing a potential new "genetic chemotherapy" approach to cancer treatment that could significantly ...
Apr 17, 2013
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Lynch Syndrome is a heritable genetic mutation that causes colorectal, endometrial and other cancers. A cooperative study that included the University of Colorado Cancer Center, published in this month's issue of the Journal ...
Feb 26, 2013
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