(Medical Xpress)—A particular kind of genetic interaction called synthetic dosage lethality (SDL) is a promising avenue for future cancer treatment, according to a study reported in the Proceedings of the National Academy ...
Scientists at the University of Massachusetts Medical School have applied a powerful tool in a new way to characterize genetic variants associated with human disease. The work, published today in Cell, will allow scientists ...
Apr 23, 2015
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Spontaneous mutations in the brain gene TBR1 disrupt the function of the encoded protein in children with severe autism. In addition, there is a direct link between TBR1 and FOXP2, a well-known language-related protein. These ...
Sep 18, 2014
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Attention deficits are central to psychiatric disorders such as schizophrenia or bipolar disorder, and are thought to precede the presentation of the illnesses. A new study led by Wayne State University School of Medicine ...
Jun 5, 2014
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Brain regions associated with memory shrink as adults age, and this size decrease is more pronounced in those who go on to develop neurodegenerative disease, reports a new study published Sept. 18 in the Journal of Neuroscience ...
Sep 20, 2013
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Cancer tumors almost never share the exact same genetic mutations, a fact that has confounded scientific efforts to better categorize cancer types and develop more targeted, effective treatments.
Sep 15, 2013
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The formation and retrieval of memories allows all kinds of organisms, including humans, to learn and thrive in their environment. Yet our memories are not always accurate, and mistaken remembrances can have important consequences, ...
Sep 13, 2013
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Scientists at A*STAR's Genome Institute of Singapore (GIS) have discovered an unusual gene that controls the generation of neurons. This important finding, which is crucial in understanding serious diseases of the brain such ...
Aug 28, 2013
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Two women have the same genetic mutation – an abnormal BRCA1 gene that puts them both at much higher-than-average risk for breast cancer – but only one woman develops the disease. Why? Michigan State University genetic ...
Aug 1, 2013
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The ability to construct complex myelin sheaths around axons is one of the greatest vertebrate inventions since the hinged jaw.
