Researchers have developed a method to swiftly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation. The technique could revolutionize modern medicine's understanding ...
Apr 3, 2017
0
39
The study, published today in Genome Biology and funded by the Medical Research Council, combined genetic sequence information with measures of gene regulation in schizophrenia patients and matched controls.
Aug 29, 2016
0
1
Dopamine signaling in the kidneys plays a critical role in blood pressure regulation and is responsible for nearly half of the salt and water excretion that occurs in response to increased dietary salt intake. Notably, genetic ...
Jun 2, 2016
0
27
What we eat can directly affect the genetic programs that regulate cellular function. A new EU project, coordinated by an LMU researcher, will explore how the products of metabolism intervene in gene regulation.
Apr 27, 2016
0
365
Scientists have made a groundbreaking discovery in understanding how the genetic complexity of tumours can be recognised and exploited by the immune system, even when the disease is at its most advanced stages.
Mar 3, 2016
0
30
Another clue to the workings of trachoma - the world's leading infectious cause of blindness - has been revealed in a new study published in BMC Infectious Diseases. Researchers identified markers of genetic regulation present ...
Feb 16, 2016
0
0
Recent investigations have shown that our genome and those of other mammals is partitioned into large functional units called topologically associated domains, or TADs for short. TADs are very long DNA sections containing ...
May 13, 2015
0
38
Scientists at the University of Massachusetts Medical School have applied a powerful tool in a new way to characterize genetic variants associated with human disease. The work, published today in Cell, will allow scientists ...
Apr 23, 2015
0
9
Using an innovative algorithm that analyzes gene regulatory and signaling networks, Columbia University Medical Center (CUMC) researchers have found that loss of a gene called KLHL9 is the driving force behind the most aggressive ...
Oct 9, 2014
0
0
Of the over 1,900 errors already reported in the gene responsible for cystic fibrosis (CF), it is unclear how many of them actually contribute to the inherited disease. Now a team of researchers reports significant headway ...
Aug 25, 2013
0
0
