A cellular profiling method called dynamic BH3 profiling (DBP), developed by investigators at Dana-Farber Cancer Institute, has the potential to help guide personalized treatment for relapsed, drug-resistant acute myeloid ...
Mar 6, 2024
0
0
Researchers have identified why some advanced estrogen receptor (ER) positive breast cancers become resistant to hormone therapy, and have identified drugs currently in development that could keep disease stable for longer ...
Feb 7, 2024
0
0
Tumors depend heavily on certain genetic changes to thrive, and researchers have discovered many such "genetic dependencies" as targets for potential new cancer drugs. At the Broad Institute of MIT and Harvard and elsewhere, ...
Jan 23, 2024
0
0
Transcription factors play essential roles in turning the genetic information encoded in genes into proteins in all cells and organisms. These regulatory proteins bind DNA, turn genes on or off, and control the rate at which ...
Dec 4, 2023
0
15
University of B.C. researchers have uncovered startling connections between micronutrient deficiencies and the composition of gut microbiomes in early life that could help explain why resistance to antibiotics has been rising ...
Nov 17, 2023
0
77
Human immunodeficiency virus (HIV) works by entering specific immune cells and replicating inside them. People with HIV are treated with antiretroviral therapy (ART), which prevents viral replication, but some individuals ...
Nov 14, 2023
0
0
A special kind of genetic test that helps determine the best antidepressant for patients with moderate-to-severe depression could generate substantive health system savings and greatly improve patient outcomes, according ...
Nov 14, 2023
0
0
Like other countries in the world, Japan has witnessed a worrisome increase in the prevalence of chronic rhinosinusitis (CRS) over the last decade. An inflammatory disease that lasts at least 12 weeks, CRS can cause nasal ...
Nov 6, 2023
0
0
Some strains of heavily antibiotic-resistant bacteria in Ghana are not successful at spreading outside of the hospital, suggesting that control measures can be focused on clinical settings to help curb treatment-resistant ...
Oct 16, 2023
0
27
Low levels of commonly used biocides, such as disinfectants and antiseptics, may increase antibiotic tolerance in Acinetobacter baumannii, a multi-drug resistant, hospital-acquired pathogen that causes serious wound, bloodstream ...
Oct 10, 2023
0
2
