A new strategy for capturing the 3D shape of the human face draws on data from sibling pairs and leads to identification of novel links between facial shape traits and specific locations within the human genome. Hanne Hoskens ...
May 13, 2021
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Sequencing the human genome was just the first step. The next challenge is of the kind that makes history: to decode the genome, and understand how the information needed to construct a human being can be packaged into a ...
Jun 18, 2012
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The St. Laurent Institute, a non-profit medical research institute focused on the systems biology of disease, today announced in a study published in the July edition of Genome Biology, that genetic matter, previously ignored ...
Jul 31, 2013
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More than 10% of older adults develop somatic (non-inherited) mutations in blood stem cells that can trigger explosive, clonal expansions of abnormal cells, increasing the risk for blood cancer and cardiovascular disease.
Feb 8, 2023
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Bacterial DNA may integrate into the human genome more readily in tumors than in normal human tissue, according to a new study from the University of Maryland School of Medicine's Institute for Genome Sciences. Researchers ...
Jun 20, 2013
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Mount Sinai researchers have cataloged thousands of sites in the brain where RNA is modified throughout the human lifespan in a process known as adenosine-to-inosine (A-to-I) editing, offering important new avenues for understanding ...
Nov 1, 2022
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An international team of researchers has now comprehensively profiled and categorized over 700 tumor samples from patients with chronic lymphocytic leukemia (CLL) by analyzing multiple levels of encoded biologic information.
Dec 6, 2021
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A tumor is not a uniform mass of identical cells. However, teasing apart genetic heterogeneity within a biopsied tumor can be difficult. Researchers often fail to tell the difference between a rare variant in a DNA dataset ...
Apr 24, 2013
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A reproducibility crisis is ongoing in scientific research, where many studies may be difficult or impossible to replicate and thereby validate, especially when the study involves a very large sample size. For example, to ...
Mar 30, 2021
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Researchers at Karolinska Institutet in Sweden have mapped how the parasite Trypanosoma cruzi forms new variants that are more effective at evading the immune system and causing disease. Their findings can give rise to new ...
May 10, 2022
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