When the human genome project was completed in 2003, some expected it to herald a new age of personalized genomic medicine, but the resulting single "reference" sequence has significant shortcomings for these applications ...
Jul 11, 2012
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Drug targets with human genetic evidence are more likely than those without to be clinically translatable and thus enter phase II/III clinical trials or be approved for marketing more quickly, which will likely significantly ...
Mar 26, 2024
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Genome-wide association studies (GWAS) look at large populations to find genes that contribute to common, multi-gene traits like height or obesity. These comprehensive investigations frequently turn up large numbers of tiny ...
May 21, 2019
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Mayo Clinic researchers studied the differences in genomic data quality among racial groups in one of the largest and most widely used cancer research datasets, The Cancer Genome Atlas.
Mar 17, 2022
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Parkinson's disease is a neurodegenerative movement disorder that progresses relentlessly. It gradually impairs a person's ability to function until they ultimately become immobile and often develop dementia. In the U.S. ...
Apr 11, 2024
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Researchers have discovered a mechanism for COVID-19 susceptibility using a newly created tool. The tool, GASPACHO, captures dynamic changes in gene expression along the innate immune response, allowing researchers to identify ...
Jun 15, 2023
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A study involving researchers from the University of Liverpool describes how transposable elements are associated with Parkinson's subtypes and impact disease trajectory.
Nov 9, 2022
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Researchers at Vanderbilt-Ingram Cancer Center have found new genes that put people at higher risk for colon cancer and rectal cancer.
Sep 13, 2023
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A new study published in Genes, Brain and Behavior has identified several genetic variants that may be linked with mathematical abilities in children.
Feb 22, 2023
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Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and 5% of these are in children. These tumors can arise ...
May 31, 2024
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