Various genetic alterations in circulating tumor cells (CTCs) were associated with clinical outcomes and resistance to hormone therapy in patients with metastatic castrate-resistant prostate cancer (mCRPC), according to results ...
Mar 26, 2021
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A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations ...
Mar 5, 2021
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Children treated for cancer with approaches such as chemotherapy can develop therapy-related myeloid neoplasms (a second type of cancer) with a dismal prognosis. Scientists at St. Jude Children's Research Hospital have characterized ...
Feb 12, 2021
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Recommendations on the use of next-generation sequencing (NGS) for patients with metastatic cancers are being launched today [25 August] by the European Society for Medical Oncology (ESMO), the leading professional organisation ...
Aug 25, 2020
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(HealthDay)—African-American (AFR) men with prostate cancer have distinct genomic alterations from European-American (EUR) men, according to a study published online July 10 in Clinical Cancer Research.
Jul 14, 2020
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A study by Vanderbilt researchers has identified genomic alterations in early stage adenocarcinomas of the lung that may indicate whether the lesions develop into aggressive tumors.
Apr 14, 2020
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Acute erythroid leukemia (AEL) is a high-risk cancer with a dismal prognosis, uncertain genetic basis and controversy surrounding the diagnosis. That is changing, thanks to research led by St. Jude Children's Research Hospital ...
Mar 29, 2019
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The largest genomic profiling study ever conducted into a type of brain tumor known as glioma in children has identified genetic alterations in 96% of cases. As reported in The Oncologist, this genetic information could help ...
Sep 14, 2017
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Being able to predict the resistance or sensitivity of a tumour cell to a drug is a key success factor of cancer precision therapy. But such a prediction is made difficult by the fact that genetic alterations in tumours change ...
Aug 14, 2017
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University of North Carolina Lineberger Comprehensive Cancer Center scientists have developed preclinical laboratory models of the two most common types of kidney cancer, an advancement that may aid in the evaluation of novel ...
Jun 9, 2017
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