Findings from an early study evaluating a sophisticated new genomic-sequencing approach that analyzes cell-free DNA (cfDNA) in the blood of people with advanced cancer will help inform development of a future assay that could ...
Jun 5, 2017
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Investigators with The Cancer Genome Atlas (TCGA) Research Network have identified novel genomic and molecular characteristics of cervical cancer that will aid in the subclassification of the disease and may help target therapies ...
Jan 23, 2017
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The use of hybrid capture-based (HC-based) next-generation sequencing (NGS) to identify targetable oncogenic drivers in patients with lung adenocarcinoma results in the detection of genomic alterations (GAs) not identified ...
Nov 17, 2016
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An international team of researchers from the St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project (PCGP) has completed a detailed map of the genomic landscape for core-binding factor ...
Oct 31, 2016
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Growing insights about a significant, yet poorly understood, part of the genome - the "dark matter of DNA"—have fundamentally changed the way scientists approach the study of diseases. The human genome contains about 20,000 ...
Oct 12, 2015
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St. Jude Children's Research Hospital scientists have developed a significantly better computer tool for finding genetic alterations that play an important role in many cancers but were difficult to identify with whole-genome ...
May 4, 2015
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The St. Jude Children's Research Hospital—Washington University Pediatric Cancer Genome Project found that melanoma in some adolescent and adult patients involves many of the same genetic alterations and would likely respond ...
Mar 5, 2015
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Genomic profiling of cancer of an unknown primary site (CUP) found at least one clinically relevant genomic alteration in most of the samples tested, an indication of potential to influence and personalize therapy for this ...
Feb 12, 2015
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Using genomic sequencing data on all currently known genetic alterations in breast cancer, it is possible to identify a woman's genetic risk for the disease, and this approach can bring greater gains in disease prevention ...
Oct 24, 2014
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The difference between merely throwing around buzzwords like "personalized medicine" and "big data" and delivering on their medical promise is in the details of developing methods for analyzing and interpreting genomic data. ...
Apr 8, 2014
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