Immunology

Why don't adrenal gland metastases respond to immunotherapy?

Recent advances in immunotherapy have allowed doctors at the University of Colorado Cancer Center to more effectively treat melanomas that spread to other parts of the body. Immunotherapy drugs such as checkpoint inhibitors, ...

Medical research

Mechanical stimuli significantly influence organ growth

In addition to chemical factors, mechanical influences play an important role in the natural growth of human organs such as kidneys, lungs and mammary glands—but also in the development of tumors. Now a research team at ...

Medical research

Pituitary gland aging can potentially be slowed down

Stem cell biologist Hugo Vankelecom (KU Leuven) and his colleagues have discovered that the pituitary gland in mice ages as the result of an age-related form of chronic inflammation. It may be possible to slow down this process ...

Oncology & Cancer

Possible origin of neuroblastoma in the adrenal glands discovered

Neuroblastoma is a childhood cancer, most commonly affecting children aged between two to three and can be fatal. Since the tumor cells resemble certain cells in the adrenal glands, a joint research group from MedUni Vienna's ...

Medical research

Crying human tear glands grown in the lab

Researchers from the lab of Hans Clevers (Hubrecht Institute) and the UMC Utrecht used organoid technology to grow miniature human tear glands that actually cry. The organoids serve as a model to study how certain cells in ...

Diseases, Conditions, Syndromes

First lab-grown mini-thyroids use patients' own tissue

Hormones produced by the thyroid gland are essential regulators of organ function. The absence of these hormones either through thyroid dysfunction due to, for example, irradiation, thyroid cancer or autoimmune disease or ...

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