Oncology & Cancer

New insight into combating drug-resistant prostate cancer

Recent research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by ...

Genetics

Genetic variant is linked to obesity and insulin resistance

A large study in people at risk of diabetes has found a direct association between the presence of a small genetic alteration in a hormone receptor and increased body fat and insulin resistance. The results, to be presented ...

Oncology & Cancer

A new route to blocking children's bone cancer

Ewing sarcoma is a bone cancer that appears mainly in teenagers. Due to a single defective gene, once it spreads to distant organs it is hard to treat. Researchers at the Weizmann Institute of Science have discovered molecular ...

Genetics

Unraveling the gene-environment interaction

A special issue of the journal Child Development reports on studies that take important new steps in understanding how genes and the environment interact in shaping child behavior.

Medications

Tailor-made pharmaceuticals as basis for novel antidepressants

The FK506-binding protein 51 (FKBP51) is an established risk factor for stress-related psychiatric disorders such as major depression. Drug discovery for FKBP51 has been hampered by the inability to pharmacologically differentiate ...

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