A single high dose of the hallucinogen psilocybin, the active ingredient in so-called "magic mushrooms," was enough to bring about a measureable personality change lasting at least a year in nearly 60 percent of the 51 participants ...
Sep 29, 2011
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(Medical Xpress) -- Psychedelic substances have long been used for healing, ceremonial, or mind-altering subjective experiences due to compounds that, when ingested or inhaled, generate hallucinations, perceptual distortions, ...
(Medical Xpress) -- In a new study published in Nature, Lisa Monteggia from the University of Texas Southwestern Medical Center looks at how the drug ketamine, typically used as an anesthetic or a popular recreational drug ...
A combined team of researchers from the Shanghai Institute of Biochemistry and Cell Biology and ShanghaiTech University's, iHuman Institute has created non-hallucinogenic analogs of LSD and psilocybin for possible treatment ...
At the molecular level, drugs like salvinorin A (the active ingredient of the hallucinogenic plant Salvia divinorum) work by activating specific proteins, known as receptors, in the brain and body. Salvinorin A, the most ...
Mar 21, 2012
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There is a new generation of drug users out there who possess highly detailed pharmacological and technical knowledge about the drugs they take. "Psychonauts" (meaning "navigator of the soul") are enthusiastic and deliberate ...
Mar 24, 2021
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Scientists at the University of Basel have shown that LSD reduces activity in the region of the brain related to the handling of negative emotions like fear. The results, published in the scientific journal Translational ...
Apr 4, 2017
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A single dose of psilocybin, the major hallucinogenic component in magic mushrooms, induces long-lasting decreases in anxiety and depression in patients diagnosed with life-threatening cancer according to a new study presented ...
Dec 10, 2015
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There is nothing magic about the recent increase in interest around the study of psychedelic drugs as potential treatments for patients suffering from a myriad of mental health conditions.
Dec 15, 2023
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Before being qualified as "magic" and becoming the global phenomenon they are today, certain mushrooms were considered as sacred by the Mesoamerican peoples of Mexico. In the Nahuatl language the word teonanacatl, literally ...
Apr 12, 2019
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This general group of pharmacological agents can be divided into three broad categories: psychedelics, dissociatives, and deliriants. These classes of psychoactive drugs have in common that they can cause subjective changes in perception, thought, emotion and consciousness. Unlike other psychoactive drugs, such as stimulants and opioids, these drugs do not merely amplify familiar states of mind, but rather induce experiences that are qualitatively different from those of ordinary consciousness. These experiences are often compared to non-ordinary forms of consciousness such as trance, meditation, and dreams.
Hollister's criteria for establishing that a drug is hallucinogenic is:
Not all drugs produce the same effect and even the same drug can produce different effects in the same individual on different occasions.
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