Each year, about 13,000 people in Germany are diagnosed with leukemia, an umbrella term that encompasses various forms of blood cancer. Among those affected are also many children and adolescents under 15 years of age. A ...
Nov 27, 2023
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Each time our cells divide, the protective caps that keep our chromosomes from fraying, called telomeres, lose a bit of their DNA. Telomeres shorten steadily as we age, but in certain medical conditions like dyskeratosis ...
Jul 7, 2023
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As a child, Lynn Aureli didn't know that a particular genetic change contributed to her acute myeloid leukemia (AML)—an alteration that eventually would help explain the cancer's lack of response to chemotherapy. Nor was ...
Jan 27, 2023
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An immunotherapy harnessing the immune system's "natural killer" cells has proven effective in treating acute myeloid leukemia (AML) in some adults whose cancers return. Now, researchers at Washington University School of ...
Dec 14, 2021
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Allogenic hematopoietic stem cell transplantation (HSCT) is a procedure that infuses a donor's healthy blood-forming stem cells into a recipient as part of a potentially curative therapy for cancer. While this therapy can ...
Aug 28, 2020
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Blood stem cell transplants—also known as bone-marrow transplants—can cure many blood, immune, autoimmune, and metabolic disorders, from leukemia to sickle-cell disease. But to make sure the healthy blood cells "take," ...
Feb 8, 2019
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A medication used to treat joint and skin conditions might also help people whose only hope of surviving cancer is receiving stem cells from a donor, according to research by a University of British Columbia scientist.
Dec 20, 2017
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Researchers at Massachusetts General Hospital (MGH) and the Harvard Stem Cell Institute (HSCI) have identified a drug compound that arrests in mice the progression of acute myeloid leukemia (AML), a bone marrow cancer that ...
Sep 16, 2016
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According to a popular saying, 'timing is everything.' For acute myeloid leukemia (AML), that adage may be true. In a paper published in the April 7 issue of Cell, an international team led by researchers from the Broad Institute ...
Apr 8, 2016
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For half a century, cancer researchers have struggled with a confusing paradox: If cancer is caused by the occurrence and accumulation of cancer-causing (oncogenic) mutations over time, young children should get less cancer ...
Jan 11, 2016
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