Cardiology

Physiological stressors triggering disease in the heart

It's not uncommon for people to live normal, healthy lives without knowledge of any underlying genetic conditions. However, all it takes is one external impact, such as a heart attack, to induce the expression of the condition. ...

Diseases, Conditions, Syndromes

Hydroxyurea may reverse sickle cell-related heart abnormalities

Heart abnormalities are common complications of sickle cell anemia (SCA) that can contribute to severe disease symptoms and even death. A study published today in the journal Blood Advances is the first to find that hydroxyurea ...

Medical research

Manufacturing spermatogonia stem cells

For species that rely on sexual reproduction, including mice and men, offspring can only happen if sperm from the male fertilize eggs from the female. Even artificial fertilization techniques depend on donors for both of ...

Medical research

Cytokine APRIL protects from atherosclerotic cardiovascular disease

Heart attacks and strokes are the main causes of death and loss of productive years globally. These clinical complications are caused by atherosclerosis, which is a chronic disease that leads to the accumulation of LDL cholesterol ...

Cardiology

Finding inspiration to rebuild human heart muscle

Advances in cardiac tissue engineering offer hope for an array of useful applications, from heart repair to disease modeling. As part of active, ongoing research related to bioengineering functional human organs, Adam Feinberg ...

Cardiology

Hypoxic inflammation blunts repair after heart attack

Inefficient cardiac repair after heart attacks is partially driven by a maladapted response to a low oxygen environment by immune cells, according to a Northwestern Medicine study published in the Journal of Experimental ...

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