Researchers trying to turn off a gene that allows cancers to spread have made a surprising U-turn. By making the gene overactive and functional in the hearts of mice, they have triggered heart cell regeneration. Since adult ...
Apr 14, 2020
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209
The commonly used chemotherapy drug doxorubicin can damage heart muscle, in some cases leading to severe or lethal heart failure. A new study led by Albert Einstein College of Medicine researchers and involving zebrafish ...
Mar 4, 2020
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108
Researchers at Osaka University used electron cryomicroscopy (CryoEM) to image essential cardiac muscle components, known as thin filaments, with unprecedented resolution. They also discovered the mechanism by which these ...
Jan 9, 2020
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51
Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body's largest protein, in real time throughout its entire lifecycle. The method and results could provide new insight into ...
Dec 13, 2019
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50
Studying mice, scientists have shown that boosting the activity of specific immune cells in the heart after a heart attack can protect against developing heart failure, an invariably fatal condition. Patients with heart failure ...
Nov 6, 2019
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Surgery can mend congenital heart defects shortly after birth, but those babies will carry a higher risk of heart failure throughout the rest of their lives. Yet, according to a Science Translational Medicine study published ...
Oct 9, 2019
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308
An international team led by scientists from Lawson Health Research Institute and Cedars-Sinai Medical Center are the first to show that Magnetic Resonance Imaging (MRI) can be used to measure how the heart uses oxygen for ...
May 30, 2019
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272
A group of researchers based in Brazil and the United States have developed a molecule that halts the progression of heart failure and improves the heart's capacity to pump blood. Rats with heart failure were treated for ...
Mar 13, 2019
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409
Changes in cellular struts called microtubules (MT) can affect the stiffness of diseased human heart muscle cells, and reversing these modifications can lessen the stiffness and improve the beating strength of these cells ...
Jun 11, 2018
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37
When it first starts to develop, the heart is a simple tube. Reporting in the journal Nature Communications, researchers at MDC have now described how it forms itself into a its characteristic S-shape and how the ventricles ...
Jun 4, 2018
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