Diseases, Conditions, Syndromes

New genetic cause of liver fat uncovered

New research has uncovered genetic variations that may contribute to the development of non-alcoholic fatty liver disease (NAFLD), the leading cause of liver disease.

Overweight & Obesity

Obesity-linked conditions are projected to rise sharply in children

Researchers' global estimates indicate that by 2025, some 268 million children aged 5 to 17 years may be overweight, including 91 million obese, assuming no policy interventions have proven effective at changing current trends.

Diseases, Conditions, Syndromes

New tool to identify persons with nonalcoholic fatty liver disease

Researchers have developed a diagnostic model that is highly predictive of nonalcoholic fatty liver disease (NAFLD). Referred to as the Framingham Steatosis Index (FSI), this novel model may become a cheaper and easier alternative ...

Overweight & Obesity

PDE4 inhibition promising tx for metabolic disorders

(HealthDay)—Inhibition of phosphodiesterase-4 (PDE4), which hydrolyses cyclic adenosine monophosphate (cAMP), may be useful for treating metabolic disorders, according to research published in the May issue of Obesity Reviews.

Diabetes

NAFLD linked to unfavorable metabolic profile in T2DM

(HealthDay)—For obese patients with type 2 diabetes mellitus (T2DM), nonalcoholic fatty liver disease (NAFLD) is associated with an unfavorable metabolic profile, according to a study published online Feb. 9 in Diabetes ...

Diseases, Conditions, Syndromes

Study links fatty liver and heart failure in obese people

Fatty liver is independently associated with subclinical heart failure in obese people, according to a new study published online in the journal Radiology. The findings add more support to the importance of dietary interventions ...

Diseases, Conditions, Syndromes

Fatty liver disease and scarring have strong genetic component

Researchers at the University of California, San Diego School of Medicine say that hepatic fibrosis, which involves scarring of the liver that can result in dysfunction and, in severe cases, cirrhosis and cancer, may be as ...

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