In mammals, the liver detects the body's energy demand at any given moment and mobilizes nutrient reserves to meet it. It is a vital function that is subdivided into multiple tasks: from releasing glucose into the blood when ...
Mar 18, 2024
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A research group from the Graduate School of Medicine and Research Institute of Environmental Medicine at Nagoya University report that cholesterol accumulation in macrophages promotes liver fibrosis in the development of ...
Sep 19, 2023
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New research presented the ESCMID Conference on Coronavirus Disease (ECCVID, online 23-25 September) shows that the severe COVID-19 immunological profile, represented by changes in cell populations and circulating inflammatory ...
Sep 25, 2020
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Hepatitis B is notoriously difficult to eradicate with currently available agents.. Now, in a new study, a novel form of "pegylated" interferon-β has reduced hepatitis B virus (HBV) infections in experimental human-derived ...
Apr 3, 2017
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SARS-CoV-2 infects and causes damage to multiple organs in COVID-19 patients. In particular, liver damage has been associated with COVID-19 severity. However, an understanding of the liver pathophysiology of these patients ...
Mar 8, 2023
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Isolated human hepatocytes are essential tools in preclinical and clinical liver research, but cell quality is highly variable. Now, researchers from Uppsala University have devised a simple protocol that improves hepatocyte ...
Dec 21, 2018
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The Asian Cancer Research Group (ACRG), an independent, not-for-profit company in collaboration with BGI, the world's largest genomics organization, and The University of Hong Kong (HKU), jointly announced the publication ...
Jul 1, 2013
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Hepatocellular carcinoma (HCC) represents a significant global health burden as one of the most common malignancies in individuals with chronic liver disease or cirrhosis. This malignancy evolves through a multistep process, ...
May 24, 2024
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For many disabling or fatal diseases, there is pre-clinical or clinical evidence of the potential therapeutic benefits of gene therapy. Unfortunately, the limitations of current gene transfer technologies have prevented successful ...
Aug 26, 2013
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Dr. Shui Guanghou's team from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has recently demonstrated that Ceramide synthases 2 (CerS2) plays a critical role in maintaining hepatic ...
Feb 15, 2022
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