Ophthalmology

Treatment options reviewed for herpes simplex viral keratitis

(HealthDay)—There is a need for development of new anti-herpetic compounds with different mechanisms of action for herpes simplex viral keratitis (HSVK), according to a review published online June 6 in Clinical & Experimental ...

Diseases, Conditions, Syndromes

Constipated? Study finds surprising cause

A Yale-led study has shown a surprising link between constipation and herpes infection. The finding, published June 8 in Cell Host & Microbe, advances the science on herpes, and could help patients with chronic gastrointestinal ...

Immunology

How antibodies access neurons to fight infection

Yale scientists have solved a puzzle of the immune system—how antibodies enter the nervous system to control viral infections. Their finding may have implications for the prevention and treatment of a range of conditions, ...

Diseases, Conditions, Syndromes

Herpes simplex virus linked to frailty, mortality

(HealthDay)—For older women, herpes simplex virus antibody levels are associated with incident frailty and mortality, according to a study published online April 30 in the Journal of the American Geriatrics Society.

Medical research

Scientists reveal new target for anti-lymphangiogenesis drugs

After an injury to tissues, such as in organ transplantation, the body grows new lymphatic vessels in a process known as lymphangiogenesis. A new study in Nature Communications reveals a mechanism involved in the regulation ...

Diseases, Conditions, Syndromes

Case of hepatitis E transmission via plasma exchange

(HealthDay)—A case of hepatitis E virus (HEV) infection has been reported in a kidney transplant recipient, according to a research letter published online March 1 in the Annals of Internal Medicine.

Medical research

Stress wakes up sleeping herpes viruses – but how?

Hiding their DNA genome inside the nuclei of the infected cells, the herpes viruses establish a lifelong infection in humans. Poorly defined stress conditions are known to wake up these parasites from their latent phase and ...

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