Research led by Peking University, China, has looked into gut microbiota production of isozymes, which do similar work to human enzymes but have different structures.
Research appearing in the Journal of Medicinal Chemistry shows for the first time SARS-CoV-2, the virus responsible for COVID-19, can be inhibited from replicating in living cell cultures using a compound that targets "Mac-1," ...
Apr 25, 2024
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A team of CiRA researchers, building upon their previous work on differentiating iPS cells into kidney organoids, have made significant improvements to build a better model of kidney development and diseases for use as a ...
Dec 1, 2023
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Assistant Professor Shunsuke Funakoshi, Associate Professor Yoshinori Yoshida, and their research team have identified Am80 as a molecule that activates the cell cycle in cardiomyocytes to enhance cardiac tissue graft production ...
Jul 14, 2023
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Scientists have revealed details of the discovery of new inhibitors of the BCL6 protein, which is involved in driving several cancer types including the blood cancer B-cell lymphoma.
Feb 9, 2023
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Pediatric encephalopathies of genetic origin cause severe motor and intellectual disabilities from birth. One of these diseases, first identified in 2013, is caused by mutations in the GNAO1 gene. In order to understand the ...
Oct 10, 2022
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A team of UC Davis Health scientists has developed a new predictive model that translates cardiac research findings across different animal species into human-specific insights. This model could help accelerate the drug development ...
Nov 17, 2021
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Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure ...
May 3, 2021
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'Mini-brains' are pin-head sized collections of several different types of human brain cell. They are used as a tool, allowing scientists to learn about how the brain develops, study disease and test new medicines. Personalized ...
Jan 7, 2021
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Many neurodegenerative conditions, from glaucoma to Alzheimer's disease, are characterized by injury to axons—the long, slender projections that conduct electrical impulses from one nerve cell to another, facilitating cellular ...
Dec 14, 2020
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