New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) is among the first to describe how an mRNA modification impacts the life of neural stem cells (NSCs). The study, published in Nature Neuroscience, ...
Jan 24, 2018
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Anyone who uses an employee badge to enter a building may understand how a protein called ENL opens new possibilities for treating acute myeloid leukemia (AML), a fast-growing cancer of bone marrow and blood cells and the ...
Mar 1, 2017
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The complex process regulating gene expression is often compared to following a recipe. Miss a genetic ingredient, or add it in the wrong order, and you could have a disaster on your hands.
Dec 15, 2016
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To "turn off" particular regions of genes or protect them from damage, DNA strands can wrap around small proteins, called histones, keeping out all but the most specialized molecular machinery. Now, new research shows how ...
Nov 28, 2016
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A single defect in a gene that codes for a histone—a "spool" that wraps idle DNA—is linked to pediatric cancers in a study published today in the journal Science.
May 12, 2016
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Neurons are a limited commodity; each of us goes through life with essentially the same set we had at birth. But these cells, whose electrical signals drive our thoughts, perceptions, and actions, are anything but static. ...
Jul 1, 2015
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Using brain tumor samples collected from children in the United States and Europe, an international team of scientists found that the drug panobinostat and similar gene regulating drugs may be effective at treating diffuse ...
May 4, 2015
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The information that interprets the genetic code in a new embryo differs depending on whether it comes from the father or mother, researchers at San Francisco State University have found.
Oct 9, 2014
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(Medical Xpress)—Virginia Commonwealth UniversitySchool of Medicine researchers have uncovered a new mechanism of action of fingolimod, a drug widely used to treat multiple sclerosis: elimination of adverse or traumatic ...
May 28, 2014
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(Medical Xpress)—Changes to a gene called LZTR1 predispose people to develop a rare disorder where multiple tumors called schwannomas form near nerve pathways, according to a study published today in the journal Nature ...
Dec 24, 2013
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