Scientists from the National Institutes of Health have identified an antibody from an HIV-infected person that potently neutralized 98 percent of HIV isolates tested, including 16 of 20 strains resistant to other antibodies ...
Nov 15, 2016
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In the first results to emerge from HIV patient trials of a new generation of so-called broadly neutralizing antibodies, Rockefeller University researchers have found the experimental therapy can dramatically reduce the amount ...
Apr 8, 2015
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A PhD student from the University of the Witwatersrand today, 12 October 2015, published a study in the prestigious journal, Nature Medicine, describing how the changing viral swarm in an HIV infected person can drive the ...
Oct 13, 2015
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A vaccine or other therapy directed at a single site on a surface protein of HIV could in principle neutralize nearly all strains of the virus—thanks to the diversity of targets the site presents to the human immune system.
May 14, 2014
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HIV is believed to have evolved from a simian immunodeficiency virus, or SIV, that originated in chimpanzees. How SIV made the species jump has remained a mystery, since humans possess a defense mechanism that should prevent ...
Apr 5, 2018
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One approach to HIV vaccine development relies on broadly neutralizing antibodies (bnAbs) that protect against different circulating HIV strains. bnAbs have been isolated from HIV-infected individuals, but they are highly ...
Aug 25, 2016
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HIV is coated in sugars that usually hide the virus from the immune system. Newly published research reveals how one broadly neutralizing HIV antibody actually uses part of the sugary cloak to help bind to the virus. The ...
Nov 23, 2011
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A study published in the Aug. 22, 2022, issue of Nature Medicine identifies a new biomarker that appears effective as a surrogate endpoint to reliably predict the ability of broadly neutralizing monoclonal antibodies to prevent ...
Aug 22, 2022
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Researchers have traced in detail how certain powerful HIV neutralizing antibodies evolve, a finding that generates vital clues to guide the design of a preventive HIV vaccine, according to a study appearing in Science Express ...
Aug 11, 2011
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In an advance for HIV vaccine research, a scientific team has discovered how the immune system makes a powerful antibody that blocks HIV infection of cells by targeting a site on the virus called V1V2. Many researchers believe ...
Mar 2, 2014
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