Oncology & Cancer

Chemotherapy drug reaches brain in humans for first time

A major impediment to treating the deadly brain cancer glioblastoma has been that the most potent chemotherapy can't permeate the blood-brain barrier to reach the aggressive brain tumor.

Genetics

Researchers discover how mutant protein leads to melanoma

Researchers from Harvard's Stem Cell and Regenerative Biology (HSCRB)'s Zon lab have discovered a new mechanism that influences melanoma development, a finding that could have wide implications for patients across a variety ...

Oncology & Cancer

Illuminating tumor cells with dark proteins

Columbia researchers have shined new light on how the "dark" part of the genome allows cancer cells to be detected by the immune system, which could lead to better immunotherapies.

Oncology & Cancer

How a virus causes chromosomal breakage, leading to cancer

The Epstein-Barr virus (EBV) is easily spread through bodily fluids, primarily saliva, such as kissing, shared drinks or using the same eating utensils. Not surprisingly then, EBV is also among the most ubiquitous of viruses: ...

Medical research

How cancer cells muscle their way into other organs

The biomechanics of how cancer cells escape from the bloodstream to invade other organs has been described for the first time by researchers from UCL, MIT and their collaborators.

Gastroenterology

Two-organ chip developed to answer fatty liver questions

A new chip that holds different cell types in tiny, interconnected chambers could allow scientists to better understand the physiological and disease interactions between organs. The integrated-gut-liver-on-a-chip (iGLC) ...

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