The impact of cohesin mutations: Insights into a hidden regulator of alternative splicing in leukemia
A new role for cohesin in regulating alternative splicing has been identified, providing insights into splicing mutations in human disease.
A new role for cohesin in regulating alternative splicing has been identified, providing insights into splicing mutations in human disease.
Bone marrow is the spongy tissue inside bone responsible for making red blood cells, white blood cells and platelets. Bone marrow failure syndromes lead to an increased risk of developing dangerous infections, anemia and ...
Mar 2, 2023
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In a first-of-its-kind study, Arizona State University Professor Michael Lynch joins a multi-institute group of researchers to investigate transcription error rates in human cells and the underlying mechanisms affecting them.
Feb 27, 2023
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Alcohol exposure in early pregnancy can change gene function during the tightly regulated embryonic development, and consequently cause developmental disorders—especially neurodevelopmental disorders. Novel information ...
Jan 3, 2023
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New drugs made from nanoparticles that can easily penetrate any interface within our bodies are a great hope in medicine. For such hopefuls to reach the market, their safety must be ensured. In this context, it must also ...
Nov 18, 2022
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Error-prone DNA replication and repair may lead to mutations and cancer in individuals who inherit a mutant copy of the BRCA1 gene, according to a new study by Weill Cornell Medicine investigators. The discovery has potential ...
Nov 15, 2022
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It was a breakthrough discovery: a protein that cuts DNA at precise points, leaving overhanging sticky ends ready to glom onto a matching partner. Using the protein, researchers could cut and paste genetic sequences from ...
Oct 7, 2022
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As we age, so do our eyes; most commonly, this involves changes to our vision and new glasses, but there are more severe forms of age-related eye problems. One of these is age-related macular degeneration, which affects the ...
Jun 14, 2022
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A new study led by a researcher in the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo has important implications for developing future treatments for Parkinson's disease (PD), a progressive ...
Jun 10, 2022
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After decades of research into the causes and treatment of Parkinson's disease, UC Irvine Health neurologist Dr. Claire Henchcliffe is hopeful that a new cell therapy can finally bring meaningful relief to patients with the ...
May 6, 2022
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