Genetics

Studying the human genome to understand the risk of autism

A team of researchers at CHU Sainte-Justine and Université de Montréal has succeeded in using bioinformatics to develop a statistical model to assess how the gain or loss of genetic material impacts the risk of autism.

Neuroscience

Why naming neurons can help cure brain disease

The human brain has about 100 billion neurons, linked in intricate ways, that the Spanish neuroanatomist Ramón y Cajal compared to "the impenetrable jungles where many investigators have lost themselves."

Genetics

Trillion data points to identify disease-causing genes

Researchers from CSIRO, Australia's national science agency, have accomplished a world-first by processing one trillion points of genomic data through VariantSpark, an artificial intelligence-based platform, which can help ...

Genetics

'Jumping' DNA regulates human neurons

The human genome contains over 4.5 million sequences of DNA called "transposable elements," virus-like entities that "jump" around and help regulate gene expression. They do this by binding transcription factors, which are ...

HIV & AIDS

Unique HIV reservoirs in elite controllers

Xu Yu, MD, Ragon group leader, recently published a study entitled "Distinct viral reservoirs in individuals with spontaneous control of HIV-1," in Nature. Yu's lab, in collaboration with Ragon group leaders Mathias Lichterfeld, ...

Oncology & Cancer

HPV strains may impact cervical cancer prognosis

An analysis of cervical cancers in Ugandan women has uncovered significant genomic differences between tumors caused by different strains of human papillomavirus (HPV), signifying HPV type may impact cervical cancer characteristics ...

Oncology & Cancer

Four-stranded DNA structures found to play role in breast cancer

Four stranded DNA structures—known as G-quadruplexes—have been shown to play a role in certain types of breast cancer for the first time, providing a potential new target for personalised medicine, say scientists at the ...

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