Researchers at the Washington University School of Medicine, St. Louis, have discovered a potential new target for cancer immunotherapy in transposable elements (TEs), short segments of DNA that can move around the genome.
Remnants of ancient viruses in the human genome are active in healthy tissues as well as diseased ones, limiting their utility as disease biomarkers, according to a study by Aidan Burn at Tufts University in Boston, U.S. ...
Oct 18, 2022
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When the human genome was sequenced, biologists were surprised to find that very little of the genome—less than 3 percent—corresponds to protein-coding genes. What, they wondered, was all the rest of that DNA doing?
Jan 25, 2013
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Like pirates on a treasure hunt, St. Jude Children's Research Hospital scientists have created the first 3-D map of a mouse genome and used it to discover scientific gold. The gold includes insight from machine learning into ...
Sep 4, 2019
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The human genome contains over 4.5 million sequences of DNA called "transposable elements," virus-like entities that "jump" around and help regulate gene expression. They do this by binding transcription factors, which are ...
Aug 31, 2020
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New research by Yale University scientists reports the discovery of "hyperhotspots" in the human genome, locations that are up to 170-times more sensitive to ultraviolet radiation (UV) from sunlight compared to the genome ...
Nov 14, 2019
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Two dozen scientific papers published online simultaneously on Feb. 18, 2015 present the first comprehensive maps and analyses of the epigenomes of a wide array of human cell and tissue types. Epigenomes are patterns of chemical ...
Feb 18, 2015
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New research from Cornell scientists is exploring how human genetics impacts functions of the gut microbiome, and is expanding awareness of the role human genetics plays in shaping the microbiome.
Apr 18, 2022
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Every cell in the human body contains a copy of the human genome. Through the course of a lifetime all cells are thought to acquire mutations in their genomes. Some of the mutational processes generating these mutations do ...
Nov 9, 2015
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The organization of the human brain develops over time, following the coordinated expression of thousands of genes. Linking the development of healthy brain organization to genes involved in mental health conditions such ...
