In 2001, researchers developed a formula, or algorithm, that predicts whether a specific change in a gene sequence can result in harmful effects. While useful, the algorithm was slow; the computations underpinning these predictions ...
May 6, 2016
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Researchers led by Ludwig Cancer Research scientist Richard Kolodner have developed a new technique for sussing out the genes responsible for helping repair DNA damage that, if left unchecked, can lead to certain cancers.
Apr 13, 2016
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Scientists have identified DNA changes that can cut a person's lifespan by up to three years.
Mar 31, 2016
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A new study that assesses the accuracy of modern human-genome-sequencing technologies found that some medically significant portions of an individual's DNA blueprint are situated in complex, hard-to-analyze regions that are ...
Mar 1, 2016
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Supposed "junk" DNA, found in between genes, plays a role in suppressing cancer, according to new research by Universities of Bath and Cambridge.
Feb 2, 2016
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Whitehead Institute researchers have created a map of the DNA loops that comprise the three dimensional (3D) structure of the human genome and regulate gene expression in human embryonic stem (ES) cells and adult cells. The ...
Dec 10, 2015
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Every cell in the human body contains a copy of the human genome. Through the course of a lifetime all cells are thought to acquire mutations in their genomes. Some of the mutational processes generating these mutations do ...
Nov 9, 2015
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Using two complementary analytical approaches, scientists at Whitehead Institute and Broad Institute of MIT and Harvard have for the first time identified the universe of genes in the human genome essential for the survival ...
Oct 15, 2015
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Growing insights about a significant, yet poorly understood, part of the genome - the "dark matter of DNA"—have fundamentally changed the way scientists approach the study of diseases. The human genome contains about 20,000 ...
Oct 12, 2015
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Our cells are up against a daily onslaught of damage to the DNA that encodes our genes. It takes constant effort to keep up with the DNA disrepair – and if our cells didn't bother to try to fix it, we might not survive. ...
Oct 9, 2015
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