Oncology & Cancer

Signature of an ineffective immune response to cancer revealed

Our immune system is programmed to destroy cancer cells. Sometimes it has trouble slowing disease progression because it doesn't act quickly or strongly enough. In a study published in The Journal of Clinical Investigation, ...

Health

How common gut bacteria trigger a lethal autoimmune disease

What causes the immune system, designed to protect us, to turn on the body and attack healthy cells? Common bacteria that reside in the human gut may be partly to blame, say Yale researchers, who studied the origins of a ...

Medical research

Molecular switch for 'exhaustion mode' of immune cells discovered

Tumors and certain viral infections pose a challenge to the human body which the immune system typically fails to handle. In these diseases it switches to a hypofunctional state that prevents adequate protection. However, ...

Immunology

A pluralistic approach to thinking about the human microbiome

In "The Conceptual Ecology of the Human Microbiome," published in the June 2019 issue of The Quarterly Review of Biology, Nicolae Morar and Brendan J. M. Bohannan examine in detail the different metaphors scientists use to ...

Medical research

How a common viral infection can lead to autoimmunity

Researchers in Dr. Leona Gilbert's research group at the University of Jyväskylä have proposed a novel mechanism for how a common viral infection could lead to an autoimmune disease. Dr. Gilbert's team demonstrated for ...

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