Oncology & Cancer

Researchers identify key source of T cell 'exhaustion'

Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies. All too often, however, they display a frustrating trait inherited ...

HIV & AIDS

Identifying where HIV sleeps in the brain

The human immunodeficiency virus HIV-1 is able to infect various tissues in humans. Once inside the cells, the virus integrates its genome into the cellular genome and establishes persistent infections. The role of the structure ...

Immunology

Study shows immune cells have a backup mechanism

The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses. Upon mutation-induced loss of TBK1 function, patients show an increased susceptibility to viral ...

Diseases, Conditions, Syndromes

Making hepatitis C care easier when treatment seems impossible

A health care team at Oregon Health & Science University is trying a different approach to caring for patients who have, or are at risk for, hepatitis C, helping overcome barriers that can otherwise make receiving testing ...

HIV & AIDS

Chronic 'jet lag' discovered in people living with HIV

People living with HIV have a significantly delayed internal body clock, consistent with the symptoms of jet lag, according to new findings reported by researchers from universities in South Africa and the U.K.

HIV & AIDS

A better understanding of how HIV-1 evades the immune system

The type of virus used as a model to study the efficacy of non-neutralizing antibodies against the virus responsible for AIDS has a crucial role to play, according to a new study led by Andrés Finzi, Université de Montréal ...

page 4 from 40