Immunology

How the thymus trains T cells to fight infections

T cells are a special class of white blood cells that patrol the body and attack infected or foreign tissue. They learn to distinguish friendly proteins from dangerous ones in an organ called the thymus. However, when T cells ...

Oncology & Cancer

Researchers design new hydrogel for more targeted cancer treatments

University of Toronto researchers have designed a new way to grow cells in a lab that enables them to better emulate cancerous tumors. The platform—based on a type of material known as a hydrogel, a soft jelly-like substance—opens ...

Overweight & Obesity

Aldose reductase promotes diet-induced obesity

High-fat diet (HFD) feeding in mice promotes induction of aldose reductase (AR) activity, expression, and senescence of adipocytes in subcutaneous adipose tissue (scAT), according to a new study in Obesity journal.

Oncology & Cancer

Lab-grown 'mini-kidneys' unlock secrets of a rare disease

Researchers have solved a medical mystery in a poorly understood disease by uncovering which cells cause tumors in patients with tuberous sclerosis complex (TSC). As described in Cell Reports, they did this by creating genetically ...

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