Huntington's disease—a hereditary and fatal genetic disorder—has long been considered a neuronal disease due to the permanent loss of medium spiny motor neurons, the death of which over time is responsible for the clinical ...
Aug 30, 2022
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Scientists from The Universities of Manchester and Auckland have discovered widespread differences in metal levels in the brains of patients with Huntington's disease, a type of dementia, compared to a control group with ...
Oct 17, 2023
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Huntington's disease (HD) is a rare disease characterized by abnormal chorea movement and caused by the Huntingtin (Htt) gene mutation and neurodegeneration in a brain area called the striatum. A research group led by Dr. ...
Feb 28, 2020
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A team with the participation of researchers from the Institute for Advanced Chemistry of Catalonia (IQAC) of the Spanish National Research Council (CSIC) has revealed the structure of the protein responsible for Huntington's ...
Apr 20, 2023
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A study from Karolinska Institutet in Sweden shows that a new drug for Huntington's disease – pridopidine or dopamine stabiliser ACR16 – might operate via previously unknown mechanisms of action. Researchers have ...
Feb 24, 2012
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(Medical Xpress)—An experiment just launched into orbit by a team of Caltech researchers could be an important step toward understanding a devastating neurodegenerative disease.
Apr 21, 2014
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Huntington's disease is caused by repeated toxic changes in the protein huntingtin. An interdisciplinary team from the Department of Molecular Neurology and the Department of Stem Cell Biology at Universitätsklinikum Erlangen ...
Dec 8, 2022
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In a paper published in the July 11 online issue of Science Translational Medicine, researchers at the University of California, San Diego School of Medicine have identified two key regulatory proteins critical to clearing ...
Jul 11, 2012
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Researchers from the Institute of Neurosciences of the University of Barcelona (UBNeuro) and the August Pi i Sunyer Biomedical Research Institute (IDIBAPS) described a mechanism, the increase of proteinaceous synthesis, which ...
Nov 21, 2019
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The Florey's Professor Anthony Hannan, Head of the Epigenetics and Neural Plasticity Group, and Research Co-Lead for the Mental Health Mission, said the results of a study published in Brain Behavior and Immunity indicate ...
Feb 2, 2024
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