Genetics

Insights into the genetic architecture of penicillin allergy

Researchers announce the first robust evidence for the role of the major histocompatibility complex gene HLA-B in penicillin allergy. To identify genetic risk factors for penicillin allergy, the international team of researchers ...

Medications

Antibody cocktail enhances clearance of SARS-CoV-2 virus

(HealthDay)—An interim analysis of data from an ongoing phase 1 to 3 trial shows that an antibody cocktail enhances clearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, according to a study published ...

Medical research

Breyanzi approved for certain types of large B-cell lymphoma

Cell-based gene therapy Breyanzi (lisocabtagene maraleucel) has been approved to treat adults with certain types of large B-cell lymphoma who have not responded to other systemic treatment, the U.S. Food and Drug Administration ...

Gastroenterology

Anti-reflux mucosectomy effective for GERD in long term

For patients with gastroesophageal reflux disease (GERD), anti-reflux mucosectomy (ARMS) shows long-term efficacy and is also effective for patients with reflux hypersensitivity, according to a study published online June ...

Medications

FDA approves first cell-based gene therapy for beta-thalassemia

The U.S. Food and Drug Administration has approved Zynteglo (betibeglogene autotemcel), the first cell-based gene therapy for the treatment of adult and pediatric patients with beta-thalassemia who require regular red blood ...

HIV & AIDS

Reactions to HIV drug have autoimmune cause, reports AIDS journal

Potentially severe hypersensitivity reactions to the anti-HIV drug abacavir occur through an autoimmune mechanism, resulting from the creation of drug-induced immunogens that are attacked by the body's immune system, according ...

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