Medical research

A metabolic switch to turn off obesity

You've tried all the diets. No matter: you've still regained the weight you lost, even though you ate well and you exercised regularly! This may be due to a particular enzyme in the brain: the alpha/beta hydrolase domain-6 ...

Neuroscience

Decoding a direct dialog between the gut microbiota and the brain

Gut microbiota by-products circulate in the bloodstream, regulating host physiological processes including immunity, metabolism and brain functions. Scientists from the Institut Pasteur (a partner research organization of ...

Neuroscience

A peek into the interplay between sleep and wakefulness

Sleep is an autonomic process and is not always under our direct, voluntary control. Awake or asleep, we are basically under the regulation of two biological processes: sleep homeostasis, commonly known as 'sleep pressure', ...

Neuroscience

Molecular duo dictate weight and energy levels

Yale University researchers have discovered a key cellular mechanism that may help the brain control how much we eat, what we weigh, and how much energy we have.

Medical research

Obese inducing brain mechanism

Leptin is an adipocyte-derived hormone that stimulates hypothalamic neurons to strongly inhibit food intake. Leptin signaling in the hypothalamus, a part of the mid-brain, thus plays a crucial role in the regulation of body ...

Neuroscience

Appetite accomplice: Ghrelin receptor alters dopamine signaling

New research reveals a fascinating and unexpected molecular partnership within the brain neurons that regulate appetite. The study, published by Cell Press in the January 26 issue of the journal Neuron, resolves a paradox ...

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