Oncology & Cancer

Immune system plays dual role in breast cancer

The immune system plays a paradoxical role in the spread of breast cancer. Some immune cells contribute to metastasis, while other cells can be activated to strengthen the effect of chemotherapy. Kelly Kersten made this discovery ...

Immunology

When suppressing immunity is a good thing

A receptor, first known for its role in mediating the harmful effects of the environmental pollutant dioxin in our body, is now understood to play other important roles in modulating the innate immune response.

Medical research

Three lessons gut microbes have taught us about antibiotics

Antibiotics have proven to be a double-edged sword: capable of killing a range of bacteria that cause infections, but also depleting our gut microbes, impairing our immune system, and increasing vulnerability to infection ...

Immunology

Compound found to trigger innate immunity against viruses

Research from UW Medicine and collaborators indicates that a drug-like molecule can activate innate immunity and induce genes to control infection in a range of RNA viruses, including West Nile, dengue, hepatitis C, influenza ...

Diseases, Conditions, Syndromes

A specially tailored gut microbiome alleviates hyperammonemia in mice

The microbiome of the human intestine consists of a variety of bacteria that assist in digestion, immune regulation, and other processes that are critical for human health. A subset of these bacteria produces urease, an enzyme ...

Immunology

Inflammatory immune cells can flip the genetic script

A type of immune cell that promotes inflammation during the immune response, TH17, can convert into another type of cell that reduces inflammation, Yale researchers have found. The finding, published April 29 in Nature, points ...

Medications

Powdered measles vaccine found safe in early clinical trials

A measles vaccine made of fine dry powder and delivered with a puff of air triggered no adverse side effects in early human testing and it is likely effective, according to a paper to be published November 28 in the journal ...

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