Genetics

A new vision for AAV-delivered gene therapies

In recent years, adeno-associated virus (AAV) has been recognized as the leading vehicle (vector) for in vivo delivery of therapeutic genes because it is non-pathogenic and efficiently targets many different cell and tissue ...

Immunology

The immune system: Knocked off balance

Instead of protecting us, the immune system can sometimes go awry, as in the case of autoimmune diseases and allergies. A Ludwig-Maximilian-Universitaet (LMU) in Munich team has dissected how mast cells regulate their calcium ...

Medical research

New testing system predicts septic shock outcomes

More than 1.7 million Americans develop sepsis each year, and more than 270,000 die from it. The condition—which happens when the body has an extreme response to a bacterial or viral infection, causing a chain reaction ...

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