Findings from St. Jude Children's Research Hospital are moving the field of cancer immunotherapy one step closer to treating brain and solid tumors. Scientists at St. Jude validated a cellular immunotherapy target called ...
Nov 21, 2023
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A new research paper has been published in Oncoscience, titled "An immunoinformatics assessment of the cancer testis antigen, DDX53, as a potential early esophageal cancer antigen."
Nov 20, 2023
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The "hygiene hypothesis" posits that allergic asthma can be triggered by a childhood environment that is too clean and sterile. One studied mechanism underlying this relationship is the influence of microbial lipopolysaccharides ...
Nov 8, 2023
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UCLA scientists have developed a new method to engineer more powerful immune cells that can potentially be used for "off-the-shelf" cell therapy to treat challenging cancers.
Nov 8, 2023
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CAR-T cell therapy is a last hope for many patients with blood, bone marrow or lymph gland cancer when other treatments such as chemotherapy are unsuccessful. A limiting factor of this otherwise very effective and safe therapy ...
Nov 6, 2023
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Mayo Clinic researchers have discovered a distinctive pattern in a specific set of 17 genes that may be associated with remission after treatment for triple-negative breast cancer. The multi-omics study, published in Breast ...
Oct 23, 2023
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Patients with X-linked severe combined immunodeficiency disorder (SCID-X1), sometimes called "bubble boy disease," are born with a defective gene that prevents them from producing immune cells. Gene therapy from St. Jude ...
Oct 6, 2023
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New research has identified a novel immunotherapy for acute myeloid leukemia. The study, published in Nature Cancer, describes a T-cell receptor that recognizes a mutation shared between a subgroup of patients with the disease. ...
Oct 2, 2023
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Chronic bowel inflammation is based on an excessive or misdirected inflammatory reaction. Experts assume that the immune system also reacts incorrectly to microorganisms in the intestine that do not cause an inflammatory ...
Sep 26, 2023
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Zachary Schug, Ph.D., assistant professor in the Molecular and Cellular Oncogenesis Program of the Ellen and Ronald Caplan Cancer Center at The Wistar Institute, has published a new paper in the journal Nature Cancer. Schug's ...
Sep 18, 2023
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