In a healthy immune system, invading pathogens trigger a cascade of alerts and responses to fight off the infection. Sensors called toll-like receptors, or TLRs, act as one of the first lines of defense. Two of these sensors, ...
Mar 14, 2012
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Misdirected immune responses that target the body's own tissue can result in diseases. regulatory T cells combat this effect by suppressing excessive immune responses and responses against our own bodies. Until now, scientists ...
Jan 8, 2015
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Nonalcoholic fatty liver disease (NAFLD) has become the most prevalent chronic liver condition worldwide, affecting about 25% of the global population due to the increasing rates of obesity and metabolic syndrome. NAFLD encompasses ...
May 24, 2024
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Investigators have identified the specific genes that become overactive as a result of nerve cell infection with Japanese encephalitis virus. The genes activate cell receptors and signaling proteins that attract immune cells ...
Jan 13, 2020
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Infections pose an increasing risk to hospitalized patients. In collaboration with a number of partners, the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB has developed a new therapeutic approach ...
Sep 1, 2020
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(Medical Xpress)—For an immune response to get underway, an invading microbe must first be halted in the spleen, and then digested by immune cells known as 'dendritic cells', which guard specific portals. Australian scientists ...
Mar 19, 2013
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Researchers at Peter Mac have overcome a major barrier that could see a revolutionary immunotherapy treatment becoming successful on patients with solid cancer types.
Apr 11, 2024
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The "hygiene hypothesis" posits that allergic asthma can be triggered by a childhood environment that is too clean and sterile. One studied mechanism underlying this relationship is the influence of microbial lipopolysaccharides ...
Nov 8, 2023
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Researchers have yet again been sent back to the drawing board in the development of the much-sought-after vaccination for smokers, which would hypothetically inhibit the action of nicotine and its pleasure-producing chemical ...
Jun 11, 2013
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A recent study from the University of Helsinki reveals that inhibiting certain adhesion receptors on the surface of dendritic cells, the main antigen-presenting cells of the immune system, enhances antitumour responses.
Oct 12, 2021
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