Cardiology

Inhibitory signal pathways identified

LMU researchers led by Christian Weber show that the chemokine receptor CXCR4 protects the integrity of arterial walls, and define a new mechanism that restricts the deleterious accumulation of cholesterol in atherosclerotic ...

Oncology & Cancer

Savior of T-cells may be enemy of liver immune cells

Researchers at Houston Methodist demonstrated that a surface protein called OX40, responsible for keeping one type of immune system cell alive, can trigger the death of liver immune cells, in turn starting a chain reaction ...

Oncology & Cancer

Vet study shows how solid tumors resist immunotherapy

Immunotherapies have revolutionized cancer treatment, offering hope to those whose malignancies have stubbornly survived other existing treatments. Yet solid tumor cancers are often resistant to these approaches.

Medications

Opioids produce analgesia via immune cells

Opioids are the most powerful painkillers. Researchers at the Charité - Universitätsmedizin Berlin have now found that the analgesic effects of opioids are not exclusively mediated by opioid receptors in the brain, but ...

Neuroscience

An antibody-based drug for multiple sclerosis

Inserm Unit U919, directed by Prof. Denis Vivien ("Serine Proteases and Physiopathology of the Neurovascular Unit") has developed an antibody with potential therapeutic effects against multiple sclerosis. The study, directed ...

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