Oncology & Cancer

How early-stage cancer cells hide from the immune system

One of the immune system's primary roles is to detect and kill cells that have acquired cancerous mutations. However, some early-stage cancer cells manage to evade this surveillance and develop into more advanced tumors.

Immunology

The 'switch' that keeps the immune system from attacking the body

A microscopic battle rages in our bodies, as our cells constantly fend off invaders through our immune system: a complex system of cells and proteins designed to protect us from harmful pathogens. One of its central components ...

Oncology & Cancer

Enzyme checkpoint identified in tumor-associated macrophages

A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in Cellular & Molecular Immunology, shows that the enzyme phosphoglycerate dehydrogenase (PHGDH) acts as a metabolic checkpoint ...

Oncology & Cancer

Predicting immunotherapy success via biomarkers

Researchers at the Technion's Ruth and Bruce Rappaport Faculty of Medicine and the Rappaport Family Institute for Research in the Medical Sciences have discovered a subset of blood cells that predict the success of immunotherapy ...

Neuroscience

Immune genes are altered in Alzheimer's patients' blood

A new Northwestern Medicine study has found the immune system in the blood of Alzheimer's patients is epigenetically altered. That means the patients' behavior or environment has caused changes that affect the way their genes ...

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