Genetics

3D genome architecture influences SCID-X1 gene therapy success

Patients with X-linked severe combined immunodeficiency disorder (SCID-X1), sometimes called "bubble boy disease," are born with a defective gene that prevents them from producing immune cells. Gene therapy from St. Jude ...

Oncology & Cancer

An ancient anti-cancer mechanism: DISE

A new editorial paper titled "DISE, an ancient anti-cancer mechanism that senses mutational load in cancerous cells?" has been published in Oncotarget.

Diseases, Conditions, Syndromes

New insights into mysterious blood vessel disease temporal arteritis

Giant cell arteritis (GCA), formerly known as temporal arteritis, was first described by Mayo Clinic doctors and classified as an inflammatory condition of the blood vessels in the early to mid-20th century. The condition ...

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